Freshman Carley Dubbert smoked a shot into the net off of a pass in the 23rd minute of the first half for her first collegiate goal of off a cross by sophomore defender Karen Nichols. The tally gave the Bulldogs a 1-0 lead in the first half.
The opening goal stood as the eventual game-winner. Junior defender Meredith Smith also assisted on Dubbert's goal.
Ferris State's triumph over Indiana Wesleyan is the Bulldogs second in as many years, as they defeated the Wildcats 2-1 in overtime last season.
In Wednesday's win, senior goaltender Maddie Haustein made eight saves in a shutout effort, with five of those shots coming in the 15 minutes following the game-winning goal.
The Bulldogs put the game out of reach in the final 10 minutes when Smith put in a shot off of assists by senior forward Casey Shauman and senior defender Hunter Dolan at 80:52. Soon after, senior forward Nichole Boehnke headed in a shot from senior defender Lindsey Scott for a beautiful goal a minute later to put the Bulldogs up 3-0.
The victory came after a pair of regional setbacks on a lengthy trip this past weekend against two highly-quality opponents in Truman State (Mo.) and Quincy (Ill.)
Ferris State generated additional scoring chances in the home opener as the put a season-high nine shots on goal against Indiana Wesleyan.
Indiana Wesleyan held a 17-16 edge in total shots for the contest, but FSU tallied seven of the 13 shots in the second half. The Wildcats were hampered by 14 fouls to only three for the Bulldogs.
Shauman paced the Bulldogs with four total shots, including a pair on goal.
Ferris State next takes on Cal State San Bernadino on Sunday (Sept. 13) in Allendale at 10:30 a.m. (ET).
FSU will then return to Big Rapids to host Aquinas on Tuesday (Sept. 15) in a special 1 p.m. (ET) afternoon start. That outing will be played at River Street Park with local elementary students set to attend.